TRPM8 (LTRPC6, TRPP8, Transient receptor potential cation channel subfamily M member 8)

Size

£735.00

SKU:: 136497
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 17aa from human TRPM8 at N-Terminal.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: TRPM8 is a receptor activated non-selective cation channel, permeable for monovalent cations sodium, potassium, cesium and the divalent cation calcium. It was originally identified due to its up regulation in prostate carcinoma. It has since been shown to be involved in the detection of coldness and is activated by icilin, eucalyptol, menthol, cold, and modulation of intracellular pH. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.