131278-FITC
Phosphodiesterase 5A (PDE5A, cGMP-Specific 3',5'-Cyclic Phosphodiesterase, cGMP-Binding cGMP-Specific Phosphodiesterase, CGB-PDE, PDE5) (FITC)
Size
£914.00
- SKU:
- 131278-FITC
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Partial recombinant protein corresponding to aa29-138 from human Phosphodiesterase 5A with GST tag. MW of the GST tag alone is 26kD.
- Clone:
- 9H5
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
- Extra Details:
- Phosphodiesterase 5A, a cGMP-specific phosphodiesterase, has been implicated in primary pulmonary hypertension, cardiac failure and erectile dysfunction. PDE5A also may function in the regulation of coronary blood flow. PDE5A is the predominant enzyme responsible for cGMP hydrolysis in trabecular smooth muscle. PDE5A activitity is inhibited by sildenafil (Viagra) and zaprinast. At least three alternatively spliced transcripts have been reported. Applications: Suitable for use in FLISA, Immunofluorescence and Western Blot. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: SVEAWLDDHWDFTFSYFVRKATREMVNAWFAERVHTIPVCKEGIRGHTESCSCPLQQSPRADNSVPGTPTRKISASEFDRPLRPIVVKDSEGTVSFLSDSEKKEQMPLTP* Storage and Stability: Store product at 4°C. For long-term storage, aliquot and store at 4°C. Aliquots are stable at 4°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice