MKNK1 (MAP Kinase-interacting Serine/Threonine-protein Kinase 1, MAP Kinase Signal-integrating Kinase 1, MAPK Signal-integrating Kinase 1)

Size

£685.00

SKU:: 129706
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Full length recombinant corresponding to aa1-466 from MKNK1 (AAH02755) with GST tag. MW of the GST tag alone is 26kD.
Clone:: 3E1
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: MNK1 is an MNK protein kinase that is activated in response to mitogens/insulin by ERK1 and ERK2, or in response to stress by activated p38. MNK1 phosphorylates eIF4E to enhance the translation rates of cap-containing mRNAs. Applications: Suitable for use in Immunohistochemistry, Immunofluorescence, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence: 10ug/ml Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml Optimal dilutions to be determined by the researcher. AA Sequence: MVSSQKLEKPIEMGSSEPLPIADGDRRRKKKRRGRATDSLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETLYQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAALDFLHTKDKVSLCHLGWSAMAPSGLTAAPTSLGSSDPPTSASQVAGTTGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTT Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.