125451-HRP
CTNNA3 (Catenin alpha-3, Alpha T-catenin, Cadherin-associated Protein) (HRP)
Size
£914.00
- SKU:
- 125451-HRP
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Full length recombinant corresponding to aa1-590 from human CTNNA3 (AAH22004) with GST tag. MW of the GST tag alone is 26kD.
- Clone:
- 3F4-1B11
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
- Extra Details:
- Alpha-catenins stabilize the cell-cell contacts by functioning as a molecular switch that regulates actin dynamics at the site of the adherens junction. Alpha-T Catenin is involved in the formation of stretch-resistant cell-cell adhesion complexes. Alpha-T catenin is expressed predominantly in cardiomyocytes, where it colocalizes with alpha-E catenin at the intercalated discs. Moreover, alpha-T Catenin is also expressed in the brain and inhibits Wnt signaling, so it is implicated in Alzheimer's disease. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: MSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATVLKDELTASLEKVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNA Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice