ARHGAP6 (Rho GTPase Activating Protein 6, Rho-type GTPase-activating Protein 6, Rho-type GTPase-activating Protein RhoGAPX-1, RHOGAP6)

Size

£685.00

SKU:: 123490
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Partial recombinant corresponding to aa531-636 from human ARHGAP6 (NP_038286) with GST tag. MW of the GST tag alone is 26kD.
Clone:: 6B3
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: ARHGAP6 (Rho GTPase activating protein 6) is similar to the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane of several cellular processes. ARHGAP6 is thought to have two independent functions, one as a GTPase-activating protein (GAP) with specificity for RhoA and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: RHADDNISKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEFSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.