CD44

Size

£486.00

SKU:: 058625
Purity:: Purified by Prrotein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponiding to aa21-220 from human CD44.
Clone:: 6G2D2
Format:: Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Extra Details:: CD44 belongs to the family of adhesion factors and is a type of transmembrane single-chain glycoprotein widely expressed on the cell surface. Originally described as a granulocyte-T lymphocyte antigen, it was named the CD44 cluster at the third international working group meeting of leukocyte differentiation antigens. CD44 is a family of glycoproteins encoded by a single gene located on chromosome 11p13. The molecular mass is between 80 and 200 kD. CD44 is highly glycosylated, including N-linked and O-linked glycosylation and chondroitin sulfate. Heparinized. CD44 is an important type of adhesion factor, which is widely distributed on the surface of lymphocytes, monocytes, endothelial cells and other cells. The diversity of CD44 ligands determines the diversity of its functions. CD44 functions as a collector of cytokines and proteases, and plays an important role in organogenesis, hematogenesis, inflammation, and autoimmune processes. As a serious disease threatening human life, tumors have received more and more attention. Early diagnosis can buy enough time for better treatment. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (FFPE): 1:50-1:200. Antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) Western Blot: 1:1000-1:40000 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice