Cav3.1 Ca2+ Channel

Size

£639.00

SKU:: 052855
Purity:: Purified by Protein A affinity chromatography from hybridoma culture.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Fusion protein corresponding to 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1, expressed in E. coli.
Clone:: N178A/9
Format:: Supplied as a liquid in 10mM Tris, pH 7.125, 50mM sodium chloride, 0.065% sodium azide. Also available carrier free, see 052855X.
Extra Details:: Voltage-dependent T-type calcium channel subunit alpha or Cav3.1 Ca2+ channel is encoded by the gene CACNA1G. Cav3.1 is a pore forming alpha subunit of T voltage-sensitive calcium channels and gives rise to T-type calcium currents. (transient opening calcium channels). These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav3.1 is expressed in various tissues including heart and smooth muscle, kidney, bone, and brain as a membrane bound protein. Diseases associated with this gene include forms of Spinocerebellar Ataxia. Applications: Suitable for use in ELISA, Immunohistochemistry, Immunocytochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice