Lysosomal Acid Lipase, Recombinant, Hamster (CHO)

Size

£1,106.00

SKU:: 052798
Molecular Weight:: 55
Purity:: ≥95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: Recombinant Hamster (CHO) Lysosomal Acid Lipase (LAL) is an essential enzyme that breaks down cholesteryl esters and triglycerides in the lysosomes, generating free fatty acids and cholesterol. These products are vital for cellular energy, membrane formation, and signaling. As an Host Cell Protein, residual LAL in biopharmaceutical products can lead to product degradation during storage or purification, impacting efficacy and safety. Therefore, careful monitoring and removal of LAL, along with other HCPs, is crucial during the manufacturing process. Recombinant protein corresponding to CHO Lysosomal Acid Lipase LAL, fused to a 6xHis-Tag, expressed in and purified from CHO cells. Accession Number: XP_035297776.1. Molecular Weight: ~55kD under reducing conditions. Coefficient Value: 2.248 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.