Syntrophin (Dystrophin-associated Protein A1 Acidic Component 1, Pro-TGF-alpha Cytoplasmic domain-interacting Protein 1, TACIP1, Syntrophin-1, SNT1)

Size

£716.00

SKU:: 052745
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane. Epitope: mapped to amino acids 108-120 within the a-syntrophin PDZ domain.
Clone:: 1351
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. For azide free antibody see 052745X.
Extra Details:: Syntrophins are a family of five 60 kD adapter proteins that use their multiple protein interaction domains (two PHDs and a PDZ) to localize various signaling proteins (kinases, ion/water channels, or NOS) to specific intracellular locations. In neurons, syntrophins are known as the postsynaptic density protein (PSD) that serves to connect neurotransmitter receptors (such as nAChRs) to the cytoskeleton. Applications: Suitable for use in Western Blot, Flow Cytometry, Immunocytochemistry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Western Blot: 0.1-5ug/ml Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.