CD167a (DDR1, Discoidin Domain Receptor Tyrosine Kinase 1, Tyrosine Kinase Receptor E, TRKE, Cell Adhesion Kinase, CAK, Neuroepithelial Tyrosine Kinase 4, NEP, NTRK4)

Size

£448.00

SKU:: 052335
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: CD167a-transfected NIH-3T3 cells
Clone:: 51D6
Format:: Supplied as a liquid in TBS, pH 8.0, 0.09% sodium azide.
Extra Details:: CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling. Applications: Suitable for use in Flow Cytometry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 1-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.