052220-PE

CD263 (TRAIL-R3, TRAIL Receptor 3, TNFRSF10C, DcR1, TRID, LIT) (PE)

Size

£691.00

SKU:: 052220-PE
Application:: Flow Cytometry
Purity:: Purified
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: TRAIL-R3-hIgGhc fusion protein
Clone:: TRAIL-R3-02
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Extra Details:: TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumor cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5). Applications: Suitable for use in Flow Cytometry Other applications not tested. Recommended Dilutions: Flow Cytometry: 1-6ug/ml Optimal dilutions to be determined by the researcher. Excitation Laser: Blue (488nm) Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.