052094

MHC Class II (I-A/I-E) (MHC Class II-Associated Invariant Chain)

Size

£748.00

SKU:: 052094
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: B6 Anti-BNL4Φ lymphocytes
Clone:: M5/114
Format:: Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Extra Details:: MHC class II-associated invariant chain (I-A/I-E), also known as Ia antigen-associated invariant chain, are single-pass type II membrane glycoproteins containing a single thyroglobulin type-I domain. They are critical components in the processing of MHC class II antigen through forming a stabilizing complex following the alpha/beta heterodimer synthesis, and orchestrating complex trafficking away from the ER compartments in which class II peptide loading occurs. Applications: Suitable for use in Western Blot, Immunohistochemistry and Flow Cytometry Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml detected MHC class II (I-A/I-E) in 10ug of mouse spleen tissue lysate. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.