048674
Synaptosomal-Associated Protein 25 (SNAP-25, SUP, Synaptosomal-Associated 25kD Protein)
Size
£607.00
- SKU:
- 048674
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Full length, unaltered SNAP-25
- Clone:
- SMI 81
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
- Extra Details:
- Synaptosomal-associated protein 25 (SNAP-25) is a component of the trans-SNARE (t-SNARE) complex. SNAP-25 has been reported to account for the specificity of membrane fusion, and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP-25 has been shown to inhibits both ATP-dependent and independent Ca2+-triggered release of glutamate from central nervous system (CNS) synaptosomal membranes. This indicates that SNAP-25 has a role not only in the formation of the synaptic vesicle-target v- and t-SNARE complex, but also in the final neurotransmitter release. Applications: Suitable for use in Western Blot and Immunohistochemistry. Though not tested, Flow Cytometry, Immunocytochemistry and Immunoprecipitation have been reported in literature. Other applications not tested. Recommended Dilutions: Western Blot: 0.5-5ug/ml Immunohistochemistry (Paraffin): 0.1-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice