TRAIL (TNF-related Apoptosis-inducing Ligand, Protein TRAIL, Apo-2 Ligand, APO2L, Apo-2L, CD253, TL2, Tumor Necrosis Factor Ligand Superfamily Member 10, TNFSF10)

Size

£500.00

SKU:: 046180
Application:: Flow Cytometry
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to a soluble fragment of residues within amino acids 95-281 human TRAIL.
Clone:: 2E5
Format:: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide
Extra Details:: Human CD253 / TRAIL (TNF-related apoptosis inducing ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2). Applications: Suitable for use in Flow Cytometry. Other applications have not been tested. Recommended Dilutions: Flow Cytometry: 1-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.