NR2F6 (Nuclear Receptor Subfamily 2 Group F Member 6, EAR2, ERBAL2)

Size

£544.00

SKU:: 046123
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to human NR2F6, expressed in E. coli
Clone:: EM-51
Format:: Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
Extra Details:: NR2F6 (nuclear receptor subfamily 2 group F member 6), also known as EAR2 or ERBAL2, is a transcription factor involved in modulation of hormonal responses. NR2F6 represses e.g. transcription of the oxytocin-neurophysin gene, renin gene, lutropin-choriogonadotropic hormone receptor gene, and the thyroid hormone receptor gene. In the immune system, NR2F6 affects IL-17 expression in the Th-17 cells, thus also the balance between immunological tolerance and autoimmunity. Applications: Suitable for use in Western Blot and Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 3-9ug/ml. Intracellular staining. Optimal dilution determined by the researcher. Western Blot Controls: Negative: HEK293T/17 cells. Positive: HEK293T/17/NR2F6/Ha-tag transfectants Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.