CD16a, Recombinant, Human, His-Tag, aa18-208

Size

£470.00

SKU:: 046047
Molecular Weight:: 22.8
Purity:: ≥95% (SDS-PAGE). Endotoxin: ≤1EU/1ug (LAL).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Extra Details:: FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody_x0002_dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-Tag at C-terminal, was expressed in insect cell and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa18-208 from human CD16a, fused to His-Tag at C-terminal, expressed in Baculovirus. Molecular Weight: ~22.8kD (200aa) Amino Acid Sequence: <ADP>MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ<HHHHHH> Biological Activity: Measured by its binding ability in a functional ELISA with Human IgG1 Fc. Applications: Suitable for use in SDS-PAGE, Bioactivity. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice