CD80 (B7-1) (PE)

Size

£460.00

SKU:: 045740
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: HTLV-1 transformed Lewis-S1 cells.
Clone:: 3H5
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Extra Details:: CD80, otherwise known as B7-1, is a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells. CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.