045393
Wortmannin
Size
£256.00
- SKU:
- 045393
- Molecular Weight:
- 428.4
- Purity:
- ≥98% (HPLC)
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- CAS Number:
- 19545-26-7
- Format:
- Supplied as a white to off-white solid.
- Extra Details:
- Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor. Synonyms: KY 12420; BRN 0067676; NSC 627609; Antibiotic SL-2052 CAS Number: 19545-26-7 Source: Penicillium sp. Molecular Weight: 428.4 Molecular Formula: C23H24O8 Solubility: DMSO, methanol, ethanol or chloroform. Slightly soluble in water. Appearance: Supplied as a white to off-white solid. Purity: ≥98% (HPLC) Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice