UNC5B,Fc, Recombinant, Human (Netrin Receptor UNC5B, UNC5H2, Protein Unc-5 Homolog 2, Protein Unc-5 Homolog B, p53-regulated Receptor for Death and Life Protein 1)

Size

£473.00

SKU:: 045381
Molecular Weight:: 80
Purity:: ≥95% (SDS-PAGE). Endotoxin: ≤0.1EU/ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder from PBS. Reconstitute with 50ul sterile ddH2O.
Extra Details:: UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling. Sequence: The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1. Specificity: Binds to mouse and human Netrin-1. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.