TRAIL-R2 (TRAIL Receptor 2, DR5, KILLER, TNFRSF10B, CD262) (FITC)

Size

£563.00

SKU:: 045357
Purity:: >95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant human TRAIL-R2 (DR5).
Clone:: HS201
Format:: Supplied as a liquid in PBS, 0.02% sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
Extra Details:: TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Applications: Suitable for use in Flow Cytometry, Immunocytochemistry Recommended Dilution: Optimal dilutions to be determined by researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.