(R,R)-Hymeglusin (1233A, F-244, L-659-699)

Size

£335.00

SKU:: 045186
Molecular Weight:: 324.4
Purity:: ≥95% (HPLC)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
CAS Number:: 29066-42-0
Format:: Supplied as a white to off-white solid.White to off-white solid
Extra Details:: beta-Lactone antibiotic. Antibacterial and antifungal. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme. Mevalonate biosynthesis inhibitor. Source: Isolated from fungal strain Scopulariopsis sp. F-244. Synonyms: (2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-2,4-undecadienoic Acid; (+)-F-(244); Antibiotic 1233A; Antibiotic F 244; F 244; Hymeglusin; L 659699; [2R-[2α(2E,4E,7R*),3β]]-11-[3-(Hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-2,4-undecadienoic Acid CAS No: 29066-42-0 Molecular Weight: 324.4 Molecular Formula: C₁₈H₂₈O₅ Appearance: White to off-white solid Purity: ≥95% (HPLC) Solubility: Soluble in methanol, ethanol, DMSO, chloroform or ethyl acetate. Insoluble in water or hexane. Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.