045129
PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040)
Size
£239.00
- SKU:
- 045129
- Molecular Weight:
- 478.7
- Purity:
- ≥95% (HPLC, NMR)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 212631-79-3
- Format:
- White to off-white solid.
- Extra Details:
- MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. Synonyms: 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide; CI-1040 CAS Number: 212631-79-3 Molecular Formula: C17H14ClF2IN2O2 Molecular Weight: 478.7 Solubility: DMSO Method for Determining Identity: Proton NMR Appearance: White to off-white solid. Purity: ≥95% (HPLC, NMR) Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice