045122
Orlistat
Size
£247.00
- SKU:
- 045122
- Molecular Weight:
- 495.7
- Purity:
- ≥98% (HPLC)
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- CAS Number:
- 96829-58-2
- Format:
- Supplied as a white to off-white solid.
- Extra Details:
- Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. Source: Synthetic. Originally isolated from Streptomyces sp. Synonyms: Tetrahydrolipstatin; Xenical; Alli; Ro-18-0647 CAS Number: 96829-58-2 Molecular Weight: 495.7 Molecular Formula: C29H53NO5 Appearance: Supplied as a white to off-white solid. Purity: ≥98% (HPLC) Solubility: DMSO, Ethanol, DMF Method for Determining Identity: HPLC and IR Storage and Stability: May be stored at 4°C for short-term only. Stable for 12 months after receipt when stored at -20°C. Protect from light and moisture. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient