045115
Okadaic acid ammonium salt (High Purity)
Size
£364.00
- SKU:
- 045115
- Molecular Weight:
- 804.018
- Purity:
- ≥98% (HPLC)
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- CAS Number:
- 155716-06-6
- Format:
- White to off-white solid.
- Extra Details:
- Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful tool for studying cellular processes that are regulated by phosphorylation. Does not affect activity of acid phosphatase, alkaline phosphatase and tyrosine phosphatase. Mimics the effects of insulin. Activates atypical protein kinase C (zeta/lambda) in 3T3/L1 adipocytes. Enhances transmitter release at neuromuscular junctions. Apoptosis inhibitor. Induces apoptosis in human breast carcinoma cells (MB-231 and MCF-7) and in myeloid cells. Neurotoxic. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling. Stimulates cell motility, loss of stabilization of focal adhesions and a consequent loss of cytoskeletal organization. Source: Prorocentrum concavum. Synonyms: Halochondrine A; CCRIS 3329; HSDB 7243; 9,10-Deepithio-9,10-didehydroacanthifolicin CAS No: 175522-42-6 Molecular Formula: C44H67O13 . NH4 Molecular Weight: 822 Solubility: DMSO, ethanol, methanol, acetone, ethyl acetate or distilled water. Dissolve first in organic solvent before diluting in water. Appearance: White to off-white solid. Purity: ≥98% (HPLC) Storage and Stability: Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Blue Ice