NU6102 (O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine)

Size

£254.00

SKU:: 045108
Molecular Weight:: 402.5
Purity:: ≥98% (NMR)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
CAS Number:: 444722-95-6
Format:: Supplied as a white to off-white solid.
Extra Details:: Potent CDK1/cyclin B (IC50 = 9.5nM) and CDK2/cyclin A3 (IC50 = 5.4nM) inhibitor. 1,000-fold more potent than NU2058. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6uM), DYRK1A (IC50 = 0.9uM), PDK1 (IC50 = 0.8uM) and ROCKII (IC50 = 0.6uM). Inhibits cell growth. Alternate Name: O6-Cyclohexylmethyl-2-(4-sulfamoylanilino)purine CAS Number: 444722-95-6 Molecular Formula: C18H22N6O3S Molecular Weight: 402.5 Purity: ≥98% (NMR) Appearance: White to off-white solid. Solubility: DMSO Method for Determining Identity: Proton NMR Storage and Stability: Store at -20°C under inert atmosphere. Protect from light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.