Notch2 (Neurogenic Locus Notch Homolog Protein 2, Motch B)

Size

£448.00

SKU:: 045101
Application:: Flow Cytometry
Purity:: >95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Recombinant mouse Notch2:Fc (AG-40B-0110).
Clone:: 16F11
Format:: Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Extra Details:: Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. Applications: Suitable for use in Flow Cytometry Recommended Dilution: Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.