LAG-3 (Lymphocyte Activation Gene-3, FDC Protein, CD223) (ATTO 488)

Size

£576.00

SKU:: 044984
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Synthetic peptide corresponding to 30aa in the N-terminus of human LAG-3.
Clone:: 17B4
Format:: Supplied as a liquid in PBS, 0.02% sodium azide. Labeled with ATTO 488.
Extra Details:: Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. Applications: Suitable for use in Flow Cytometry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:100 Optimal dilutions to be determined by researcher. Excitation (Max): 501nm Emission (Max): 523nm Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: ATTO 488 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.