IL-37, Recombinant, Human, His-Tag (Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1)

Size

£453.00

SKU:: 044945
Molecular Weight:: 30
Purity:: ≥95% (SDS-PAGE). Endotoxin: <0.01EU/ug (LAL).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with 100ul sterile ddH2O.
Extra Details:: IL-37 (IL-1F7) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth. Recombinant protein corresponding to aa1-218 of human IL-37, fused to His-Tag at C-terminus, expressed in E. coli. Molecular Weight: ~30kD (SDS-PAGE) Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.