GITR, Recombinant, Mouse,Fc (Tumor Necrosis Factor Receptor Superfamily Member 18, Activation-inducible TNFR Family Receptor, Glucocorticoid-induced TNFR-related Protein, CD357, TNFRSF18, AITR)

Size

£576.00

SKU:: 044846
Molecular Weight:: 45
Purity:: >95% (SDS-PAGE)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2. Reconstitute with 50ul sterile ddH2O.
Extra Details:: GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway. Sequence: Mouse GITR (aa 20-152) is fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.