DLL1, Recombinant, Mouse,Fc (Delta-like Protein 1, Delta 1)

Size

£384.00

SKU:: 044747
Molecular Weight:: 100
Purity:: ≥90% (SDS-PAGE). Endotoxin: ≤0.1EU/ug (LAL)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder from PBS. Reconstitute with 50ul or 100ul sterile ddH2O
Extra Details:: The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor. Recombinant protein corresponding to the signal peptide and extracellular domain of mouse DLL1 (aa1-545) fused at the C-terminus to the Fc portion of human IgG1, expressed in HEK293 cells. Swiss/UniProt Accession: Q61483 Biological Activity: Inhibits adipogenesis of 3T3L-1 cells. Induces Hes-1 in 3T3L-1 cells. Specificity: Interacts with Notch receptors Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.