044717
Cyclopamine
Size
£243.00
- SKU:
- 044717
- Molecular Weight:
- 411.6
- Purity:
- ≥98%
- Storage Conditions:
- 4°C/-20°C
- Supplier:
- United States Biological
- CAS Number:
- 4449-51-8
- Format:
- Supplied as a white to off-white solid.
- Extra Details:
- Cell permeable steroidal alkaloid. Specific sonic hedgehog signaling (Shh) pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer. Synonyms: 11-Deoxyjervine; 11-Deoxojervine; HSDB 3505 CAS Number: 4449-51-8 Source: Veratrum californicum Molecular Weight: 411.6 Molecular Formula: C27H41NO2 Solubility: Ethanol, methanol, DMF or DMSO. Insoluble in water. Appearance: Supplied as a white to off-white solid. Purity: ≥98% Storage and Stability: Store at 4°C. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Shipping Conditions:
- Ambient