Asc (Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5)

Size

£576.00

SKU:: 044570
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa at the N-terminal human Asc.
Format:: Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Extra Details:: Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases. Applications: Suitable for use in Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot. Other applications not tested. Recommended Dilutions: Immunocytochemistry: 1:200 Immunohistochemistry: 1:500; paraffin sections Immunoprecipitation: 1:200 Western Blot: 1:1000 Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.