(25S)-delta7-Dafachronic acid

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£462.00

SKU:: 044440
Molecular Weight:: 414.6
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 949004-12-0
Extra Details:: Ligand of DAF-12, an orphan nuclear receptor, that regulates dauer diapause, reproductive development, fat metabolism, and life span (life cycle) in parasitic nematodes. Sterol-derived hormone. Blocks formation of infective larvae in several parasitic nematodes. Inhibits the dauer-promoting activity of DAF-12. Supports the reproductive development. Synonyms: UPF-1404; (5α,25S)-3-oxo-cholest-7-en-26-oic acid CAS No: 949004-12-0 Molecular Formula: C27H42O3 Molecular Weight: 414.6 Purity: ≥95% (HPLC) Appearance: White to off-white solid Solubility: Highly soluble in DMSO. Soluble in ethanol or methanol. Only slightly soluble in water, dichloromethane or acetone Identification: 1H NMR Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.