10Z-Hymenialdisine

Size

£473.00

SKU:: 044433
Molecular Weight:: 324.1
Purity:: ≥97% (HPLC) (Contains traces of the 10E-isomer)
Storage Conditions:: 4°C/-20°C
Supplier:: United States Biological
CAS Number:: 82005-12-7
Format:: Supplied as a solid.
Extra Details:: Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor. Source: Axinella carteri Synonyms: Hymenialdisine; 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one CAS No: 82005-12-7 Molecular Weight: 324.1 Molecular Formula: C₁₁H₁₀BrN₅O₂ Method for Determining Identity: Proton NMR Solubility: DMSO Appearance: Supplied as a solid. Purity: ≥97% (HPLC) (Contains traces of the 10E-isomer) Storage and Stability: Store at -20°C under inert atmosphere. Caution: Light-sensitive. For maximum recovery of product, centrifuge the original vial prior to removing the cap.