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042258

SPR, CT (SPR, Sepiapterin reductase)

Size

£696.00

SKU:
042258
Purity:
Purified by Protein A affinity and peptide affinity chromatography.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within aa231-260 in the C-terminal region of human SPR, UniProt Accession #P35270.
Format:
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice