034809
DSC3, CT
Size
£696.00
- SKU:
- 034809
- Purity:
- Purified by Protein A and peptide affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 822-850 from the C-terminal region of human DSC3.
- Format:
- Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
- Extra Details:
- The protein encoded by this gene is a calcium-dependent_x000D_ glycoprotein that is a member of the desmocollin subfamily of the_x000D_ cadherin superfamily. These desmosomal family members, along with_x000D_ the desmogleins, are found primarily in epithelial cells where they_x000D_ constitute the adhesive proteins of the desmosome cell-cell_x000D_ junction and are required for cell adhesion and desmosome_x000D_ formation. The desmosomal family members are arranged in two_x000D_ clusters on chromosome 18, occupying less than 650 kb combined._x000D_ Alternative splicing results in two transcript variants encoding_x000D_ distinct isoforms. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice