CREBL1, CT (ATF6B, CREBL1, G13, Cyclic AMP-dependent transcription factor ATF-6 beta, Activating transcription factor 6 beta, Protein G13, cAMP response element-binding protein-related protein, cAMP-responsive element-binding protein-like 1, Processed cyclic AMP-dependent transcription factor ATF-6 beta)

Size

£696.00

SKU:: 034211
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: REBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-600 amino acids from the C-terminal region of human REBL1.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: CREBL1 is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.