CDX2, phosphorylated (S283) (CDX2, CDX3, Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2)

Size

£696.00

SKU:: 033734
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Phospho-CDX2-S283 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 268~297 amino acids surrounding S283 of human CDX2.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM 600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription. Applications: Suitable for use in Immunofluorescence, Dot Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Dot Blot 1:500 Immunofluorescence: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.