IL10 (IL10, Interleukin-10, Cytokine synthesis inhibitory factor)

Size

£633.00

SKU:: 031049
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified His-tagged IL10 protein (fragment).
Clone:: 530CT10.5.7
Format:: Supplied as a liquid, 0.09% sodium azide.
Extra Details:: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~400 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.