ESR2, ID (ESR2, ESTRB, NR3A2, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2)

Size

£633.00

SKU:: 030953
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: ESR2 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human ESR2.
Clone:: 555CT18.5.5
Format:: Supplied as a liquid, 0.09% sodium azide.
Extra Details:: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~4000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.