AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II)

Size

£633.00

SKU:: 030749
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: AGT antibody is generated from mouses immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human AGT.
Clone:: 656CT5.8.4
Format:: Supplied as a liquid, 0.09% sodium azide.
Extra Details:: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:200~800 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice