LSD1/AOF2 (lysine (K)-specific demethylase 1A, Lysine-specific histone demethylase 1A)

Size

£576.00

SKU:: 030408
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant fragment of human LSD1 expressed in E. coli.
Clone:: 1B2E5
Format:: Supplied as a liquid, 0.03% sodium azide.
Extra Details:: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kD) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin. Applications: Western Bloting: 1:500-1:2000. Immunofluorescence: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.