JAK3 (Janus kinase 3)

Size

£588.00

SKU:: 030355
Purity:: Ascites
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified recombinant protein fragment corresponding to aa116-328 from human JAK3, expressed in E. coli.
Clone:: 5H2
Format:: Supplied as a liquid, 0.03% sodium azide.
Extra Details:: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). Applications: Suitable for use in Immunofluorescence, Flow Cytometry, ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:100-1:500. Immunofluorescence: 1:200-1:1000. Flow Cytometry: 1:200-1:400. ELISA: 1:10,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.