029982
AXL (AXL Receptor Tyrosine Kinase, UFO, JTK11)
Size
£607.00
- SKU:
- 029982
- Purity:
- Ascites
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein extracellular fragment corresponding to aa19-444 from human AXL, fused with hIgGFc-tag, expressed in HEK293 cell line.
- Clone:
- 7E10
- Format:
- Supplied as a liquid, 0.03% sodium azide.
- Extra Details:
- AXL is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in ELISA, Western Blot and Immunocytochemistry/Immunofluorescence. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:2000 Immunofluorescence (IC): 1:200-1:1000. ELISA: 1:10,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice