029588
PRDM14, NT (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)
Size
£787.00
- SKU:
- 029588
- Application:
- WB
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to the N-terminus of human PRDM14, fused to GST-Tag.
- Format:
- Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
- Extra Details:
- PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 detected PRDM14 in 10ug of human lung tissue lysate. Optimal dilutions to be determined by the researcher. Positive Control: Human lung tissue lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice