Thapsigargin

Size

£479.00

SKU:: 021685
Molecular Weight:: 650.75
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 67526-95-8
Format:: Off-White Solid
Extra Details:: A widely used inhibitor of the ubiquitous sarco-endoplasmic reticulum Ca(2+)-ATPases in mammalian cells. It acts as a potent, cell-permeable, IP3-independent intracellular calcium releaser that blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. It induces apoptosis by disrupting intracellular free Ca2+ levels. Form: Off-White Solid Melting Point: 84-90°C Solubility: Chloroform