Physostigmine

Size

£403.00

SKU:: 019677
Molecular Weight:: 275.35
Purity:: ≥99%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 57-47-6
Format:: White to pale orange solid
Extra Details:: A parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying. Physostigmine is an alkaloid and noted to act as a potent and reversible inhibitor of cholinesterase. Physostigmine is also reported to form a slowly degrading carbamylated enzyme complex with AChE (acetylcholinesterase). This compound has been used as a positive control in a study investigating acetylcholinesterase inhibitors for potential antihelminthic drug targets. Synonyms: (3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol Methylcarbamate Ester; Eserine; Synapton; Cogmine; Eserine; Esromiotin; MCV 4484; NIH 10421; NSC 30782; (3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl methylcarbamate CAS Number: 57-47-6 Molecular Formula: C₁₅H₂₁N₃O₂ Molecular Weight: 275.35 Appearance: White to pale orange solid Purity: ≥99% Melting Point: 102-106°C Solubility: Chloroform (Slightly, Sonicated), DMSO (Slightly), Ethanol (Slightly), Methanol Storage and Stability: Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.