PF 431396

Size

£358.00

SKU:: 019167
Molecular Weight:: 506.5
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 717906-29-1
Format:: Supplied as a gray solid.
Extra Details:: PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats. Synonyms: N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; N-Methyl-N-[2-[[[2-[(2-oxo-_x000B_2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide; PF 431396 CAS Number: 717906-29-1 Molecular Weight: 506.5 Molecular Formula: C₂₂H₂₁F₃N₆O₃S Solubility: DMSO (Slightly) Appearance: Supplied as a gray solid. Melting Point: >214°C (dec.) Storage and Stability: Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Pfizer Compound