Nalidixic Acid-d5

Size

£448.00

SKU:: 017961
Molecular Weight:: 237.27
Storage Conditions:: RT
Supplier:: United States Biological
Format:: Crystalline Powder
Extra Details:: Inhibitor of bacterial DNA synthesis. Nalidixic acid is the first of the synthetic quinolone antibiotics. It is a naphthyridone, not a quinolone: its ring structure is a 1,8-naphthyridine nucleus that contains two nitrogen atoms, unlike quinoline, which has a single nitrogen atom.[1] Synthetic quinolone antibiotics were discovered by George Lesher and coworkers as a byproduct of chloroquine manufacture in the 1960s.[1] Used clinically from 1967.[1] Nalidixic acid is effective against both gram-positive and gram-negative bacteria. In lower concentrations, it acts in a bacteriostatic manner; that is, it inhibits growth and reproduction. In higher concentrations, it is bactericidal, meaning that it kills bacteria instead of merely inhibiting their growth. Form: Crystalline Powder Melting Point: 229-230°C Solubility: Chloroform, Ethanol, Methanol, Toluene