Isoniazid

Size

£364.00

SKU:: 015047
Molecular Weight:: 137.14
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 54-85-3
Format:: White Solid
Extra Details:: Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antibacterial (tuberculostatic). Form: White Solid Melting Point: 167-169°C Solubility: DMSO, Methanol